"Biseptolum": how effective is the "grandmother's" cure for "all diseases"

Biseptol has been known for more than a dozen years. In Soviet times, it was the most popular drug for almost any disease of an infectious nature, it is both adult and child, its price is not high, and the drug is effective. Gradually, he was replaced by new drugs with a large spectrum of action and effectiveness. But today, Biseptol does not lose its relevance, and the reviews of doctors confirm this.

Composition and principle of action

When is biseptol used and how much should I drink? One Biseptol 120 mg tablet contains 100 mg sulfamethoxazole, 20 mg trimethoprim and additional components. Accordingly, a dose of 240 mg or 480 mg contains two and three times more active substances. The combined effect of the components of the drug is aimed at inhibiting the formation of folic acid in the bacterial cell. Substances are selected in such a way that enhance the action of each other. This adds to the effectiveness of the drug.

Its action is as follows:

• sulfamethoxazole - has a structure similar to para-aminobenzoic acid, due to which it interferes with the formation of folic acid;
• trimethoprim - slows down the transition of vitamin B9 precursors to the active form.

Due to this, minimal concentrations of folic acid are created, which is essential for the growth and development of bacteria. “Biseptol” in high concentration causes the death of pathogens sensitive to it and, thus, eliminates the infection.

The activity of the drug extends to the following microorganisms:

• E. coli;
• streptococci;
• staphylococci;
• pneumococci;
• typhoid and dysentery bacteria;
• gonococci;
• salmonella;
• hemophilic bacillus;
• Klebsiella;
• enterococcus;
• chlamydia
• toxoplasma;
• Leishmania.

The tool does not act on Pseudomonas aeruginosa and tubercle bacillus, leptospira, spirochetes and viruses.

When to use

Modern doctors "Biseptolum" is prescribed for pathologies caused by pathogenic microbes susceptible to the effects of sulfamethoxazole. The method of application is indicated in the table.

Table - Conditions in which the use of Biseptol tablets and powder for injection is recommended

Contraindications

After taking "Biseptolum" quickly penetrates into the systemic circulation and after three to five hours reaches its maximum concentration. Metabolized in the liver. High concentrations of the drug are created in the kidneys, since it is mainly excreted in the urine. Contraindications for admission are as follows:

• hypersensitivity to the components of the drug;
• complex forms of heart failure;
• pathology of the liver with damage or death of its cells;
• renal failure;
• anemia caused by a lack of folic acid;
• pathology of blood and bone marrow;
• bronchial asthma;
• hay fever;
• atopic (allergic) dermatitis.

Biseptol should not be taken if the patient has had an immunological decrease in platelet count in the past caused by taking the drug.

The components of the drug help to reduce the content of folic acid and can lead to its deficiency. In addition, the use of the drug in the third trimester of gestation can contribute to the occurrence of nuclear jaundice in the fetus. Therefore, "Biseptolum" during pregnancy and during breastfeeding is categorically contraindicated for use, and its children should not be used for up to three months.

Instructions for use "Biseptolum"

The dosage of "Biseptolum" and the duration of use are prescribed by the doctor individually in each case. You can take a convenient form, the dosage regimen does not differ in the amount of active substance.

Biseptol is available in tablets of 120 (for children) and 480 mg, in the form of syrup and suspension in ampoules for oral administration. Schemes for using various forms of medication are described in the tables.

Table - How to take "Biseptolum" depending on age

Tablets or suspension should be taken after meals with clean, still water. The course of admission lasts up to 14 days. If therapy lasts more than five days, it is recommended to monitor blood counts. With abnormal fluctuations, up to 10 mg of folic acid per day is additionally prescribed.

Depending on the variety and severity of the infectious process, the standard dosage of Biseptolum may vary, as can be seen from the table.

Table - Separate Biseptol administration regimens

In severe forms of the infectious and inflammatory process, the doctor can double the dose.

Side effects and overdose

The instructions indicate good tolerability of the drug and a minimal risk of side effects. But still, the following can be distinguished:

• nausea, vomiting, and diarrhea;
• headache, dizziness;
• tendency to depression;
• inflammation of the peripheral nerves;
• bronchial cramps, asthma attacks and coughing;
• obstructed outflow of bile;
• acute inflammation of the large intestine;
• a decrease in the level of neutrophils (agranulocytosis);
• a decrease in the number of white blood cells and platelets in the blood;
• deficit Vitamin B12 and folic acid;
• severe allergic dermatitis;
• the appearance of blood in the urine, crystalluria.

People with HIV infection are more likely to have side effects.

special instructions

When taking "Biseptolum" there is a risk of salt crystals in the urine and the formation of kidney stones, therefore, to prevent such side effects throughout the treatment, it is necessary to use a sufficient amount of fluid and monitor the tests.

The simultaneous use of the drug with diuretics increases the risk of hypokalemia (lowering potassium in the blood) and bleeding. For the period of treatment, it is recommended to completely abandon alcohol so as not to provoke toxic hepatitis. With prolonged therapy, it is necessary to take tests to monitor the functional state of the kidneys, liver and monitor hematological parameters.

Analogs

Analogues for the active ingredients are the following drugs:

• Bactrim
• Septrin
• "Sumerolim";
• “Berlocide”;
• "Ceplin";
• "Co-trimoxazole."

Reviews on the drug "Biseptolum" prove its effectiveness in relation to many diseases. Despite the availability and popularity of the drug, it should be taken as prescribed by the doctor. Even the treatment of cystitis or pharyngitis with Biseptolum is fraught with an overdose or the acquisition of resistant forms of microorganisms.

Reviews

I consider Biseptol to be an old, reliable, proven drug that helps in solving the problems of not only sick respiratory organs, but also abscesses, barley, and also diarrhea. He treated himself and his children with success. I know that it is bad for the liver, so I consumed it only after eating and drinking milk. In the battle with bronchopulmonary diseases, it is necessary to take 4 tablets per day, 2 tablets at an equal interval for 3-5 days, depending on the severity. For ulcers, 1-2 single doses of 2 tablets are sufficient, and he saves from diarrhea from one intake in the same number of tablets. Wonderful drug!

Olga M., https://protabletky.ru/biseptol/#otzivi

I know that this antibiotic has been used for a long time. And he was, in principle, a traditional medicine for many diseases. And I had to test it on myself about 10 years ago. But my experience with this drug is a little negative. I’ll say why - I had an attack of kidney disease. I was just at the sanatorium. The doctor attributed this antibiotic to me. With the kidneys, however, everything became normal, but I got a thrush when I arrived home. I didn’t even know what it was. I went to my doctor and told me everything. And he explained to me that after treatment with Biseptol our bacteria are killed and you can get sick thrush. So then I treated another and try not to use it anymore.

Elizabeth T., https://protabletky.ru/biseptol/#otzivi

I took this drug for many years, took it on the road, from poisoning, and yesterday I nearly threw back my hooves, thanks to resuscitation. For 10 minutes, the whole face was swollen with a pulse of more than 200, the whole was covered with a rash, the tongue could not speak at all, so be careful - many take this drug on vacation. Previously, there was no allergy to biseptol or other drugs.

Dmitriy, http://www.tiensmed.ru/news/biseptolusi1.html

Since childhood I have been treated with Biseptolum. I believe him only, perhaps. In general, any medicine always has a side effect. And a leaflet, as well as a doctor’s consultation, together with the results of the tests, are the best prevention of any side effects of any medicine.

Irina, http://www.tiensmed.ru/news/biseptolusi1.html

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