The content of the article
Genital candidiasis, or thrushcaused by fungi of the genus Candida. They are attributed to the conditionally pathogenic flora of the mucous membranes; they are found in smears of healthy women. However, in the presence of certain pathogenic factors, fungi begin to multiply intensively. The main provocateurs of the occurrence of thrush in women are:
- taking antibacterial drugs of systemic action;
- endocrine diseases (diabetes mellitus, hypothyroidism);
- intestinal dysbiosis;
- poor nutrition, hypovitaminosis;
- weakening of immunity due to diseases, taking medications;
- local use of antiseptics, cosmetics;
- pathology of the reproductive system (myomainfection).
Such manifestations of thrush, such as itching, cheesy discharge and discomfort during sexual intercourse, significantly worsen the patient's quality of life and can adversely affect relations with a partner. If you need a way to get rid of thrush - acute, chronic, or relapsing - many women choose Diflucan.
What is the drug
The main task of the gynecologist is the choice of an effective drug that has an effect as soon as possible. "Diflucan", the active substance of which is fluconazole, will quickly eliminate the symptoms of candidiasis and at the same time has a high degree of safety. Capsules contain 50 or 150 mg of the active ingredient. The price of the drug in pharmacies is usually low.
Diflucan is produced by the famous American company Pfizer. He has long established himself in the pharmaceutical market as a medicine with clinically proven efficacy. The main active ingredient, fluconazole, in its composition belongs to the antifungal pharmaceuticals of the triazole group.
The mechanism of action of Diflucan is a violation of the synthesis of sterols in the cell wall of the fungus. Moreover, it acts strictly selectively on the sterol compounds of the pathogen. In the conducted studies, no effect of fluconazole on the synthesis of sterols in the human body was found.
Fluconazole is effective against the following species of fungi of the genus Candida:
- Candida Albicans;
- Candida Tropicalis;
- Candida Glabrata;
- Candida parapsilosis.
Also in medical experiments, it was found that this drug is effective in cryptococcosis, microsporosis, trichophytosis, histoplasmosis and other fungal infections.
Release Forms
A pharmaceutical company produces a medicine both for oral administration (oral administration) and for administration directly into the human body, i.e. parenterally. The following forms of Diflucan are on sale.
- Capsules (tablets). They may contain different amounts of the main active substance: 0.05; 0.1; 0.15 g
- Lyophilisate for suspension. One milliliter of a suspension prepared from Diflucan powder contains 0.01 g of fluconazole.
- Injection. One milliliter of Diflucan injections contains 0.002 g of fluconazole.
Diflucan candles for women are not available. However, in pharmacies there are other antifungal drugs in the form of suppositories or ointments.
After taking capsules or suspensions, the active substance is rapidly absorbed in the gastrointestinal tract. It is best to take the medicine in between meals, in which case it is more rapidly absorbed. The maximum therapeutic concentration of fluconazole in the blood is determined after an hour and a half.
This drug is very well distributed practically in all tissues of the human body. However, its greatest content is detected in the skin and mucous membranes.
"Diflucan": instructions for use
In gynecological practice, Diflucan is used to treat genital candidiasis. Indications for use in this case are:
- vaginitis;
- vaginosis;
- vulvovaginitis.
"Diflucan" can be used from a fungus as an independent drug, or as part of combination therapy for mixed infections. Also, fluconazole is prescribed as a prophylaxis of mucosal candidiasis in women taking antibiotics.
Given that "Diflucan" is well distributed in all tissues of the body, it is used for fungal infections of a different location:
- gastrointestinal mucosa;
- bronchopulmonary system;
- urinary system (cystitis, urethritis);
- eyes, oral cavity and pharynx;
- external integuments, nails, with pityriasis versicolor;
- generalized infection with damage to internal organs, skin and mucous membranes.
Diflucan is also used to treat diseases caused by other fungal infections. It is shown with:
- coccidioidomycosis;
- paracoccidioidomycosis;
- sporotrichosis;
- histoplasmosis;
- cryptococcosis with damage to the meninges, skin, internal organs.
Schemes for vaginal candidiasis
For the treatment of acute vaginal candidiasis (thrush), a single use of the drug is sufficient. You need to drink one capsule (0.15 g) of Diflucan. The capsule is swallowed whole, before meals or after meals, with plenty of water.
Treatment of exacerbation of chronic candidiasis "Diflucan" is carried out according to the following scheme: it is taken in a dosage of 0.15 g once. After three days, another such capsule should be taken. "Diflucan" helps very well with thrush, after the first intake of the capsule itching, burning in the vagina are eliminated, discharge is reduced.
In the chronic course of vaginal candidiasis, exacerbations can be prevented with the help of Diflucan. In this case, take 0.15 g of fluconazole once a month. Such therapy can last up to a year.
How to treat other fungal infections
Treatment of other fungal pathologies is carried out according to the scheme presented in the table.
Table - Therapy of fungal infections
| Disease | Dosage | Duration of Admission |
|---|---|---|
| Cryptococcal infection | - 0.4 g on the first day; - then 0.2-0.4 g once a knock | - 6-8 weeks |
| Generalized candidiasis | - 0.4 g on the first day; - then 0.2 g each | - Until the disappearance of clinical symptoms |
| With candidiasis of the mouth (stomatitis) | - 0.05-0.1 g once a day | - 1-2 weeks |
| With candidiasis of the intestine and other parts of the digestive tract, damage to the respiratory system | - 0.05-0.1 g once a day | - 2-4 weeks |
| Mycosis of the skin | - 0.15 g once a week | - 2-4 weeks |
| Pityriasis versicolor | - 0.3 g once a week | - 2 weeks |
| Cryptococcal infection | - 0.4 g on the first day; - then 0.2-0.4 g once a knock | - 6-8 weeks |
Therapy for pediatric patients
For the treatment of fungal infections of the mucous membranes in children, powder is used to prepare the Diflucan suspension. The drug is bred in four steps.
- Boil a small amount of water (about 50 ml).
- Open the powder bottle.
- Add 0.024 L of chilled boiled water to the powder.
- Close the bottle cap and shake well.
How is the drug transferred
According to doctors, Diflucan is very well tolerated by patients. Occasionally, the following side effects may occur:
- allergic manifestations (skin rash, angioedema);
- headache, sleep disturbance, anxiety;
- vestibular disorders;
- vomiting, nausea, bloating, stool disorder;
- skin rashes, hair loss;
- muscle pain
- heart rhythm disturbance.
When not appointed
Contraindications to taking the medicine are:
- individual intolerance;
- reception of "Terfenadine", "Erythromycin", "Quinidine";
- impaired sugar metabolism;
- lactase deficiency.
Acquisition and analogues
"Diflucan" refers to an over-the-counter group of drugs. It can be freely bought at any pharmacy chain. In the absence of "Diflucan" on sale, it can be replaced by other analogues, also containing fluconazole:
- «Flucostat»;
- "Diflason";
- "Fluconazole Teva";
- Mikomaks.
The scheme of use of these drugs does not differ from that of Diflucan. However, when buying an analogue, you should definitely pay attention to the dosage of the main active substance. How many women need to take this remedy for thrush is interesting. The treatment regimen should be determined and prescribed only by a specialist, it is individual for each patient, depending on his age and condition.
Reviews of "Diflucan" with thrush suggest that it is a fairly effective antifungal drug. It quickly eliminates the signs of the disease in women and is safe enough. Today, Diflucan capsules are one of the most popular drugs in gynecological practice.
Loading...