"Doxycycline": why a long-forgotten antibiotic is good

"Doxycycline" in a pharmacy can be found both in the form of a lyophilisate (used for intramuscular / intravenous administration), and in the form of capsules for internal use and. However, the first method of treatment is rarely used.

How does the medicine work?

As part of "Doxycycline" is the same active substance. The drug belongs to tetracyclines, has a wide spectrum of activity. "Doxycycline" acts bactericidal - leads to the death of microbial cells. The drug penetrates the cells and acts on pathogens here. "Doxycycline" disrupts the synthesis of protein microbes, which leads to their death. It is active against the following microorganisms:

• pathogens of purulent infectious diseases - Golden and epidermal staphylococcus, streptococcus;
• pathogens of intestinal infections - Clostridia, Listeria, Klebsiel, Escherichia coli, Enterobacter, Salmonella, Yersinia, Vibrio cholera;
• genital infections - gonococci, pale treponema (causes syphilis), chlamydia, mycoplasmasureaplasmas.

In addition, the drug acts on the causative agents of brucellosis, ornithosis, tularemia, anthrax, psittacosis, legionellosis.

Capsules and ampoules

Before prescribing the drug, it is recommended to determine the sensitivity of the microbes that caused the disease. For this, sowing is carried out from the place of concentration of pathogens, for example, from the vagina, pharynx, nose, sputum. The main diseases that are indications for the use of "Doxycycline" are presented in the table.

Table - When doxycycline is used

Who should not take side effects

Doxycycline treatment is prohibited in the following cases:

• allergic reactions to the drug - It is also necessary to consider cross-allergy with drugs of the tetracycline and penicillin group;
• blood diseases - leukemia, leukopenia, porphyria;
• impaired liver - the main transformation of the drug occurs in the organ;
• pregnancy and lactation - "Doxycycline" easily penetrates the placental barrier, into breast milk and the baby, it is proved that the drug disrupts the formation of bone tissue, teeth in children.

Side effects after taking Doxycycline are presented in the table.

Table - Side effects of the drug

Given the risk of complications, the use of Doxycycline capsules (and especially injections) is possible only as directed by a doctor. In case of an overdose, the manifestation of side effects increases, there is no specific treatment, symptomatic therapy is carried out.

Instructions for use "Doxycycline"

The drug is available in ampoules for the preparation of a solution for intramuscular and intravenous administration, but the most popular form of use is capsules for oral administration. Intravenous and intramuscular administration is indicated only in cases of severe purulent-inflammatory diseases. For this, the contents of the ampoule are dissolved in a sterile isotonic solution.

The dosage of Doxycycline tablets can be 50, 100 and 200 mg of the active substance, ampoules of 100 or 200 mg. Standard treatment regimens are as follows:

• 100 mg every 12 hours - within 7-14 days;
• 200 mg every 24 hours - within 7-14 days;
• 300 mg every 24 hours - within ten days (only for the treatment of syphilis).

For the prevention of malaria and the treatment of rosacea, acne, the drug is used for a long time, courses of a month or more.

special instructions

Doctors' reviews prove that to prevent adverse reactions and other complications, it is necessary to consider the compatibility of Doxycycline with other drugs and alcohol used. The following drug interactions are known:

• penicillins, cephalosporins - "Doxycycline" reduces the effectiveness of these drugs;
• alcohol, barbiturates, Rifampicin, Carbamazepine - lead to a decrease in the concentration of "Doxycycline" in the blood and tissues, therefore dose adjustment is required;
• indirect anticoagulants - correction of their dose is required while taking with an antibiotic.

Additional recommendations

To prevent complications of taking "Doxycycline", the following recommendations should be followed:

• do not sunbathe - during the use of tablets and another week after the end of the course of treatment, ultraviolet rays should be avoided due to hypersensitivity to them during this period;
• take tests - with long-term use of "Doxycycline", for example, when it is prescribed for the prevention of malaria or acne treatment, general and biochemical blood tests should be monitored, since changes are possible in them;
• make sure there is no pregnancy - "Doxycycline" violates the formation of the skeleton in the fetus in utero and in young children.

Analogs

The following drugs are full analogues of the drug in composition, dosage, indications, side effects:

• Unidox Solutab;
• "Vibramycin";
• "Novacyclin";
• Doxybene
• "Medomycin."

"Doxycycline" is one of the effective drugs for the treatment of inflammation in the genitourinary system, intestinal and other infections. However, reviews of Doxycycline in ampoules and capsules indicate a high incidence of side effects of the drug. In particular, from the gastrointestinal tract - nausea, vomiting, dysbiosis. Before taking it, it is important to consult a doctor, make sure that there are no contraindications.

Reviews: “Do not take the capsule on an empty stomach!”

As the instructions say many side effects, one of them is esophagitis, which I received on the 10th day of the drug. I developed two large esophageal ulcers, which I then had to treat for a long and expensive time. If there are options for taking other drugs, it is better to take them.

Gennady, https: // www. piluli. com / product / Doksiciklin / review

Cystitis is tortured, once again you are afraid to go somewhere without tablets for a long time. Doxycycline removed the symptoms in a few hours (I was able to go to the toilet normally and without pain), but I must go through the entire course of treatment. I drink the third day after eating, as the doctor said, and there is no vomiting, dizziness, nausea, everything is fine. It is very inexpensive, I hope that after the end of the course I will forget about this disease forever.

Zhanna Naumova, https: // www. piluli. com / product / Doksiciklin / review

I passed the smear and after a while the result was already in my hands - ureaplasma was positive. I was very upset, the gynecologist explained that due to the presence of ureaplasma, problems with conception can occur. My spouse and I took according to the scheme: in the morning and in the evening, take one capsule, respectively 5 days. In addition to taking antibiotics, it was necessary to observe sexual rest, monitor hygiene. And a month after treatment, it was necessary to repeat the analysis for infection. The biggest mistake I made was that they took the drug incorrectly. Never take the capsule on an empty stomach! Only after eating. On the first day, we drank the capsule on an empty stomach. Immediately dizzy, became sick. After treatment, ureaplasma was no longer detected.

Irina lee, http: // irecommend. com / content / borba-s-ureaplazmoi-planirovanie-beremennosti

The drug, surprisingly, very well helped in the treatment of the upper respiratory tract, was very surprised by its low price and high efficiency, took it after meals and drank up to 1.5 liters of water a day so that the intestines would not be damaged.

Natalya Chepurnaya, https: // health. mail. com / drug / doksitsiklin /

Prescribed doxycycline after a miscarriage in order to avoid all kinds of genital infections. Bad stuff inexpressible. In addition to all other symptoms, bleeding opened, and the gastrointestinal tract was almost ruined (literally twisted in half from the vomiting). I consulted with the district police officer, she replied that everything under control was just minor side effects. My jaw fell off in place. As a result, she urgently changed both the doctor and the antibiotic. I had to sit on a porridge and kefir for a long time to restore the digestive tract.

Nina k, https: // protabletky. com / doxycycline / # otzivi

Other medications