Duspatalin tablets in the treatment of diseases of the digestive system

Pain syndrome of various intensities (from severe pain to minor discomfort in the abdomen) is an invariable companion of functional diseases of the gastrointestinal tract (GIT). Most often, it is caused by a spasm of smooth muscle fibers, which are many in the walls of hollow organs. That is why, in the treatment of such pathologies, agents are prescribed that relax smooth muscles. Instructions for use "Duspatalin" describes that this drug belongs to this group of drugs. How and when should it be used?
Box of Gastric Pills

Diseases of the gastrointestinal tract take second place in frequency of occurrence after pathologies of the respiratory system. An important point is the fact that the bulk of patients with digestive system disorders are young and middle-aged people. It is in them gastrointestinal diseases that reduce the quality of life, limit professional activity, becoming the cause of psychological discomfort. Not compatible with alcohol.

In the treatment of such conditions, the main place is given to the restoration of impaired motility of the digestive tract and the elimination of pain. In this case, drugs are shown that purposefully affect the smooth muscle cells of the stomach, intestines, bile ducts.

What is the drug

Is Duspatalin an antibiotic or not and can they be given to pregnant women? Duspatalin tablets contain mebeverine hydrochloride as the main active ingredient, which eliminates spasms in the gastrointestinal tract. Its mechanism of action is the ability to act on the following structures of smooth muscle cells:

  • sodium channels - block them, reduce the entry of sodium into the cell and eliminate spastic contractions;
  • calcium channels - stabilize them and prevent atony from the appearance of atony of the walls of the digestive tract.

Moreover, Duspatalin does not affect the normal intestinal motility and does not interfere with its functioning.

The drug "Duspatalin" is available in the form of small capsules in which mebeverine hydrochloride is in granular form. A feature and advantage of this dosage form is that the mebeverine microspheres have a double layer. The outer layer is a substance resistant to the effects of acidic gastric contents, and the inner is an active component with a prolonged effect. The content of mebeverine in Duspatalin capsules is equal to 0.2 g. In addition, the composition of the medicine includes:

  • compounds of methacrylic, ethacrylic acid;
  • fillers;
  • magnesium stearate.

The capsule shell itself consists of gelatin with the addition of titanium oxide.

After taking the drug inside, its membrane is destroyed, and the medicine enters the liver through the portal vein system. The hydrolysis of the active component occurs in the liver cells, therefore, the drug remains are not found in the patient’s blood. The drug is excreted mainly through the urinary system, a small percentage - through the liver and biliary tract.

In what cases is prescribed

The main indication for the use of this drug is a disease of the gastrointestinal tract, which are based on functional disorders. Indications for the use of Duspatalin are as follows:

  • chronic stoneless cholecystitis;
  • gallstones
  • postcholecystectomy syndrome;
  • biliary dyskinesia;
  • colitis, enterocolitis, colic;
  • constipation or diarrhea (diarrhea);
  • irritable bowel syndrome.

Also, the medicine is used for gastroduodenal reflux, gastritis, duodenitis, gastroduodenitis, pancreatitis. In case of gastric or duodenal ulcer, Duspatalin is taken only as directed by a doctor. Usually it is recommended after the acute process subsides. According to doctors, the use of this medication for diseases of the gastrointestinal tract allows you to achieve the following effects:

  • eliminate abdominal pain of varying severity;
  • reduce nausea, vomiting, belching;
  • restore the motor function of the digestive tract.

Also, Duspatalin tablets help eliminate the concomitant symptoms of digestive disorders: bitterness in the mouth, nausea, flatulence, impaired appetite.

Pain after taking Duspatalin is stopped on the third day of treatment. After a week's use of the drug, the motor activity of the gastrointestinal tract is restored. It is important that even prolonged use of Duspatalin does not cause any significant side effects. Therefore, it is often recommended for long courses in diseases of the gastrointestinal tract.

Instructions for use "Duspatalin"

How many days to drink and how to take? According to the official instructions for use, this drug is recommended to be taken before meals. The interval between taking the capsule and food should not exceed 20 minutes. Drink the medicine with a sufficient amount of water, at least 100-150 ml per day.

The usual dosage of Duspatalin is 0.2 g (one capsule) twice a day. How long the course of treatment with Duspatalin lasts is usually determined by the doctor based on the clinical situation.

If you have missed taking the medicine, you should not drink immediately the next double dose. It is better to continue to take Duspatalin as usual according to the doctor’s recommendations.

What are the side effects?

Reviews of Duspatalin indicate that it rarely causes side effects. Occasionally, against the background of its use, the following consequences may be observed:

  • vestibular disorders;
  • allergic manifestations (urticaria, Quincke's edema);
  • rarely - anaphylactic shock.

When taking very large doses of the drug, an overdose may occur. In this case, the side effects of Duspatalin are manifested by signs of overexcitation of the central nervous system. As a first aid, gastric lavage is performed and adsorbents are prescribed to eliminate poisoning. In a subsequent patient, symptomatic treatment is performed.

When the medicine is contraindicated

The main contraindication to the treatment with Duspatalin is individual intolerance to the main active substance - mebeverin. It is also not recommended to use this medicine for the prevention of any gastrointestinal disorders, for example, after overeating or dietary disorders. Like any other medicinal substance, mebeverin should not be taken with alcohol.

Despite the fact that there are no proven facts of the harmful effects of Duspatalin on the developing fetus, nevertheless, it should not be taken independently during pregnancy. It is better to consult your doctor and adhere to his recommendations. In the case of breastfeeding, you can take the medicine in the usual dosage, since it does not get the baby with mother's milk.

Satisfied woman with a purchase at the pharmacy

Where to buy and what are the analogues

Duspatalin can be bought freely at any pharmacy. For this, it is not necessary to have a doctor's prescription on hand. The cost of one package of the drug averages 520-640 rubles (data for December 2017). The cost depends on the number of capsules in the package and the trade margin. In the absence of the original drug in the pharmacy, you can buy its analogues:

  • Mebeverin;
  • Sparex
  • Niaspam.

As the main active substance, they contain mebeverine hydrochloride. These pharmaceuticals can be used in the same dosages as Duspatalin.

Duspatalin tablets are an effective pharmacological tool that allows you to quickly eliminate pain, nausea, discomfort in the abdomen. Since they act selectively on the smooth muscle cells of the gastrointestinal tract, they are deprived of most of the side effects characteristic of other myotropic drugs. Therefore, Duspatalin can be used for a long time, without fear of any negative consequences for the body.

Other medications

Article updated: 06/10/2019

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