Monural: antibiotic benefits in treating urinary tract infections

Most often, women suffer from cystitis and pyelonephritis. Features of the anatomy (short and wide urethra) contribute to the rapid and unhindered entry of microbes into the bladder and then ascending to the kidneys. Particularly dangerous are UTIs (urinary tract infections) in pregnant women. "Monural" is a modern broad-spectrum antibacterial drug used to treat inflammatory diseases of the urinary system.

Composition and activity

The main active substance in the composition of the drug is fosfomycin. It is a derivative of phosphonic acid. In addition, the preparation also has auxiliary components, such as sucrose, saccharin and additives with the taste of orange and mandarin.

Monural is produced in white granules, from which a solution for oral administration is prepared. Packaged in 2 g and 3 g sachets. Effective against both gram-negative and gram-positive flora. Namely:

• Escherichia coli;
• enterococcus;
• staphylococcus;
• Klebsiella;
• Proteus, pseudomonas.

Monural is ineffective in the presence of genital infections, such as gonorrhea. And also with the detection of ureaplasmas, chlamydia, mycoplasma. In this case, it is necessary to combine several drugs.

Fosfomycin has an effect due to the following mechanisms.

• Release agent. Prevents the penetration of pathogenic microorganisms into the epithelium lining the urinary tract.
• Bactericidal. It disrupts the synthesis of proteins in a bacterial cell, as a result of which its further development stops and death occurs.

Indications

The drug is prescribed for the following conditions:

• cystitis - acute form, chronic relapse;
• severe bacteriuria - the presence of pathogenic microorganisms in the urine without symptoms;
• bacterial urethritis - characterized by burning, pain during urination;
• for infection prevention - after and during the planning of diagnostic procedures and surgical intervention on the organs of the urinary system.

Treatment for pregnant and lactating

Expectant mothers can take the drug according to strict indications. Cystitis and other diseases of the urinary system are frequent companions of an "interesting position". Therefore, if there is a threat to the health of a woman or a baby, the doctor can advise Monural.

The manufacturing company claims that the drug does not affect the fetus or the course of pregnancy. Its plus is a minimum of contraindications. Side effects are extremely rare. It is important to consider whether there were episodes of inflammation of the urinary organs in a woman before pregnancy.In case of chronic infection, the combined use of drugs is recommended.

If necessary, use "Monural" in a nursing woman at the time of treatment, lactation is interrupted, and the milk is decanted.

Scheme

Granules must be diluted in 1/3 cup of water or other liquid (juice, compote) before use. The medicine is taken at night before bedtime two hours before / after a meal or on an empty stomach. It is first necessary to urinate. Dosage:

• acute inflammation - 3 g once;
• for prevention - 3 g before the intervention (three hours), 24 hours after the initial dose, another 2 g;
• children after five years - 2 g once (it is better to use the drug after 12 years).

Elderly people with severe diseases with a relapsing course are recommended to take the drug again in the same dose after 1 day.

Contraindications, side effects and complications

The drug is prohibited in the following conditions:

• hypersensitivity to one of the components of the drug;
• age up to five years;
• severe renal failure.

The following side effects from taking an antibiotic are described:

• dizziness and headache;
• fatigue;
• paresthesia;
• increased heart rate;
• thrush in women;
• manifestations of allergies (itching, rash);
• heartburn;
• bouts of nausea;
• vomiting

For the prevention of fungal vulvovaginitis anti-candidal suppositories are used before and after the course of treatment.

Cases of development of antibiotic-associated colitis are described. If there are appropriate complaints (abdominal pain, stool disturbance, the appearance of blood and mucus in the feces), you should consult a doctor and undergo appropriate treatment.

Be sure to consider

When using Monural, the following points must be considered.

• Time of receipt. The absorption of the drug decreases with the simultaneous use of food. Therefore, it is taken two hours after or before meals, as well as on an empty stomach.
• Drug interaction. It is not recommended to take this antibiotic with Metoclopramide, as the latter helps to reduce the concentration of fosfomycin in the body.
• Caution with an increase in blood glucose. In diabetes mellitus, it is necessary to remember the presence of sucrose in the preparation (2.213 g per sachet). It is undesirable to use for people who do not tolerate sucrose-isomaltose or fructose.
• Driving and alcohol. Caution should be exercised while driving a vehicle or controlling other mechanisms, since there is no data that would confirm the absence of the effect of the drug on the reaction rate. Also, the interaction of the drug with alcohol is unknown.

Monural must be kept out of the reach of children. It is suitable for three years, the temperature regime is up to 30 ° С.

Reviews

In my practice, I use Monural as an emergency medicine in the treatment of inflammation of the bladder (cystitis, pyelocystitis). The drug has good sensitivity to intestinal infections. One bag is enough to relieve acute manifestations of inflammation of the bladder. In anticipation of the summer and trips to the sea, I recommend having it with you.

Urologist Hestanov S.N., https://protabletky.ru/monural/#otzivi

I’m 8 months old, found E. coli in urine, prescribed Monural. I drank it as it should, at night, according to the instructions. After 4 hours I woke up. The worst diarrhea, directly water, vomiting. All day diarrhea, today is the second day after taking. Diarrhea, but at least the nausea has passed. I hope that at least it will help, and that the baby will not harm. So consider it my fly in the ointment in your ointment.

Lyudmila R., https://protabletky.ru/monural/#otzivi

The treatment of cystitis must be approached very carefully. And the main thing is not to be treated on your own. And then I began to be treated with an antibiotic which was treated for the flu and made it worse. But it turned out, as the doctor explained, that the body had developed stability. They prescribed me a monural, which was created to treat cystitis. So I drank and really helped a lot. He relieved me of cystitis and symptoms. Now I’m not self-medicating.

Marina, http://www.tiensmed.ru/news/monural-ab1.html

Other medications