"Rumikoz": antimycotic activity, regimens, side effects

Available in the form of capsules of five to six pieces in a blister. Capsules have a white base and a lid of a brown hue, inside are spherical granules of a yellowish color. The active substance is itraconazole. It destroys the cell membranes of fungi, as a result of which they do not multiply and cease to exist. In one capsule - 100 mg of itraconazole.

Drug features

"Rumikoz" is active against dermatophytes, as well as infections provoked by yeast, yeast-like and mold-type fungi. The active substance after entering the blood plasma is concentrated in the digestive tract (especially in the liver, stomach), renal pelvis, lung tissue, bones and skeletal muscle. But an even greater content of the drug is observed in keratinous tissues - the skin and its derivatives. Therefore, capsules are widely used to treat fungal infections of the nails, epidermis. The rate of elimination of the drug from the tissues depends on their renewal. The data are shown in the table.

Table - The rate of removal of itraconazole from tissues

"Rumikoz" is also used as an anti-inflammatory agent. In addition to itraconazole, it includes:

• titanium dioxide;
• gelatin;
• poloxamer;
• azorubine.

Indications

The drug has a wide focus. It is prescribed for:

• cutaneous mycosis;
• fungal infection of the scalp under the scalp;
• mycosis of internal organs;
• pityriasis versicolor;
• candidiasis of any form and localization (including thrush of the mucous membrane of the mouth and genitals);
• cryptococcosis or sporotrichosis, as well as histoplasmosis;
• fungal keratitis (damage to the lining of the eyes).

Contraindications

The use of the drug is not recommended for patients with individual intolerance to its components. Also in the list of contraindications include:

• heart disease
• renal dysfunction;
• hepatic dysfunction.

The medicine is contraindicated in children. The tool is categorically incompatible with alcohol.

Pregnancy and lactation

Capsules are prescribed to expectant mothers in cases where the intended benefits of the medicine exceed a significant threat to the fetus. Despite the fact that the accumulation of "Rumikoz" occurs mainly in the layers of the skin, it acts systemically and can penetrate the placental barrier.

During lactation, it should be borne in mind that itraconazole passes into milk. If treatment is necessary, it is recommended to switch to artificial feeding.

Treatment regimens

For maximum absorption, the drug should be drunk immediately after eating. Depending on the problem, different dosage of medication is prescribed, as can be seen from the table.

Table - Schemes for taking "Rumikoz"

Adverse reactions

With the right dosage, adverse reactions are extremely rare. But sometimes itraconazole provokes side effects. The list of possible:

• digestive tract disorders - lack of appetite, discomfort, dyspepsia, anorexia;
• elevated liver enzymes - as well as hepatitis, acute liver failure;
• headaches - as well as dizziness, peripheral neuropathy;
• allergic manifestations - including photosensitivity, Quincke's edema.

special instructions

Calcium channel blockers can reduce the force of contraction of the heart, so it is important to be careful when taking it in parallel with itraconazole.

Patients using antacids need to drink them two hours after "Rumikoz", since the absorption of itraconazole slows with a decrease in acidity.

Those who suffer from achlorhydria, use proton pump inhibitors or H2 blockers, it is recommended to drink the antifungal medicine with acidic drinks to prevent a decrease in its effectiveness.

Analogs

The drug can be replaced with analogues, which include:

• «Irunin»;
• Itrazol;
• "Itraconazole";
• "Orungamine";
• "Mikonyhol";
• Orungal;
• "Candidral."

These medicines also contain 100 mg of itraconazole as the active substance, have similar indications, contraindications and side effects.

Reviews

If you thrush and you are allergic toflucostat anddiflucan and you can’t stand candles, then you just have to go to the pharmacy and buy Rumikoz, as I do. In general, it is expensive, 6 tablets per 300 r. That is, for the treatment of one course, just 6 tablets are needed, but there is also a shortened course for two days.
The instructions describe in detail how to take it, etc. I have no side effects on him. Used throughout my life 4 times and always helped. Good, effective drug, I liked it. Moreover, apart from candles, I have no other choice, the rest is allergic. He has not fluconazole in his composition, but itraconazole, itraconazole is better for me. Symptoms quickly relieves, of course, you can additionally put a candle, but I do not.

Frank, http://xlebez.ru/protivogribkovoe-sredstvo-rumikoz/

I am preparing for the treatment of postpartum cervical erosion - I treat inflammation. Only Candida was revealed, and not many, single ones, as the doctor said. First tried Livarol with fluconazole - in vain. Then this Rumikoz was appointed. I also asked the doctor if anything was needed locally. She replied that this is already a fairly strong drug. It was checked after months. And what - my single fungi in place. I must say that I did not feel any side effects while taking the drug - neither lightheadedness, nor nausea, nor rash. But after the end of the reception, my hair fell terribly - 300-500 a day. I have suffered before, but not on such a scale. In the instructions, alopecia (baldness) is indicated as a side effect. And it continues to this day (more than a month has passed). They say to me - "if that were the case, then you would have gone bald." And I'm balding - the parting is wider, the scalp glows. Bitterly….

Marina, http://xlebez.ru/protivogribkovoe-sredstvo-rumikoz/

At one of the gynecologist’s receptions, I found out about Rumikoz. Prescribed to take it 2 tablets per day, a course of 6 days. In the package where 100 mg is the price of 434 rubles, which is not very cheap.
I needed 2 such packages for the course (which came to me 868 rubles).
Initially, the doctor told me that they should be taken only with a severe exacerbation, i.e., severe itching and white watery discharge of a milky color with an unpleasant odor (sorry for frankness). And so, the time has come, the reception began.After the first two tablets in the evening, I felt very sick, so I decided to lower the dose in the following days. After a course of treatment (6 days), the thrush left me in about 10 days. But besides nausea, another small surprise was waiting for me - there was a delay of 10 days! This is a lot for my body, in which everything happened like a clock.

Streight, http://irecommend.ru/content/zaderzhka-mesyachnykh-obespechenapredlagayu-bolee-deshevyi-analog

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