The content of the article
This drug was first registered in 1957 by a Swiss pharmaceutical company. Now Solcoseryl is used in medical practice in 50 countries and is included in the protocols for the treatment of most diseases.
This drug has been successfully used in various branches of medicine: in traumatology, neurology, cardiology, hematology, dentistry, ophthalmology, gynecology. Over many decades, extensive experience in its application.
Solcoseryl - Solcoseryl - is known as a drug used to quickly and effectively heal wounds, burns and trophic ulcers. And since the patient had a chance to encounter him, he is interested in everything - which is more effective: solcoseryl ointment or parenteral routes of administration, whether solcoseryl is suitable for internal use, whether it is possible to smear the nose with solcoseryl, is it hormonal, is it in injections ... Why should we you will not try to study this drug in more detail - who prescribes it, why and why.
What is this medicine
Pharmacologically, the drug is hemodialysate from the blood serum of dairy calves. The composition of Solcoseryl includes a wide range of cell components having a low molecular weight. 1 ml of the finished medicinal product contains 0.0425 g of dry matter - biologically active ingredients:
- involved in metabolism - alanine, ornithine, leucine;
- neurotransmitters- glycine, choline, taurine, glutamt;
- pyrimidine bases - uridine, adenosine.
In addition, Solcoseryl contains trace elements that affect the functioning of an enzyme important for the body - superoxide dismutase. This enzyme has an antioxidant effect, is involved in the neutralization of free radicals.
The source for this drug is the blood serum of dairy calves grown on farms in Australia and New Zealand. In these regions, there have been no reported cases of prion diseases in animals that can cause spongiform encephalopathy in humans.
How does it work
The drug has a complex effect on damaged tissues, it contributes to faster cell regeneration, prevents their apoptosis (programmed cell death). As a result, Solcoseryl has the following therapeutic effects:
- angioprotective;
- trophic;
- antioxidant;
- reparative.
In many ways, these effects of the drug are due to the presence of serofendic acid in it.Some of its components have a number of biologically important properties:
- bind free radicals;
- participate in the regulation of apoptosis;
- contribute to the differentiation of cells;
- reduce the concentration of calcium inside the cells;
- participate in lipid peroxidation;
- contribute to the synthesis of myelin (sheath of nerve fibers);
- have an antiplatelet effect;
- restore blood vessels.
What are the types
Given the widespread use of this medicine in medical practice, it has various forms of release:
- pills;
- injection;
- gel and ointment for topical application;
- dental paste.
Solcoseryl tablets (dragees) may contain 40, 100 or 200 mg of the main active ingredient. They are taken orally according to the schedule prescribed by the doctor.
The solution for injection is available in ampoules of different volumes (2 or 5 ml). However, the concentration of the main active substance in them is the same (0.0425 g in 1 ml).
Also for local use in pharmacies you can buy ointment and Solcoseryl gel. The tubes with the medicine are relatively small, only 20 g. Depending on the form of release, the ointment or gel may contain different concentrations of the main active substance - 2.07 or 4.15 mg, respectively. In addition to the main component, they include preservatives and stabilizers.
The advantage of the gel is its good absorbency, it is easily washed off and leaves no residue on clothing. However, the use of ointment is more preferable in the formation of a protective crust on the surface of the wound. Thus, a protective film is created and reparative processes occur faster.
Indications for appointment
The drug is widely used in the treatment of various pathological processes associated with tissue ischemia, trophic disorders, traumatic and inflammatory injuries. The most common indications for the use of Solcoseryl are:
- acute and chronic cerebrovascular pathologies - a group of brain diseases caused by pathological changes in cerebral vessels with impaired cerebral circulation;
- acute head injuries - and residual phenomena after them;
- erosive and ulcerative lesions of the gastrointestinal tract - for example, the solution is used to heal stomach ulcers, hemorrhoids;
- pathology of the vessels of the lower extremities- obliterating atherosclerosis, trophic disorders;
- trophic disturbances - with diabetic angio-and polyneuropathy, after frostbite, wounds and abrasions, damage to the skin during burns;
- radiation damage - as well as conditions after transplantation of the skin;
- lesions of the oral mucosa - of various genesis (gingivitis, periodontal disease, stomatitis).
Instructions for use "Solcoseryl"
Depending on the form of release of Solcoseryl, there are various treatment regimens.The exact dosage of the drug is best to check with your doctor first.
Pills
The standard dosage of Solcoseryl tablets is 100 mg, it is taken up to three times a day. It is recommended to drink the medicine in between meals. The duration of pill therapy is determined by the doctor.
Solution
This release form is for injection only. The medicine can be administered intravenously drip or jet, as well as intramuscularly. Before the drip of Solcoseryl, the contents of the ampoule are pre-diluted in 250 ml of physiological saline. You can also use a 5% glucose solution in the same amount.
If you intend to administer the drug intravenously, then you must again dilute it with saline or glucose solution. In this case, a proportion of 1: 1 should be observed.
The dosage of the drug depends on the severity of the course and the type of disease. The table shows the data on how Solcoseryl is used in ampoules for various diseases.
Table - The use of the solution "Solcoseryl" for injection
| Disease | Amount of medicine | Multiplicity of application |
|---|---|---|
| Obliterating peripheral vascular disease (stage III-IV) | 20 ml | - 1 per day; - duration of therapy for at least a month |
| Peripheral vein circulatory failure | 10 ml | - 3 times a week; - duration of therapy for at least a month |
| Cerebrovascular pathology, traumatic brain injury (TBI) | 10-20 ml | - 1 per day; - duration of therapy - 10 days |
| The consequences of head injury, stroke | 2 ml | - Once a day; - duration of therapy for at least a month |
Gel and ointment
Gel or ointment "Solcoseryl" is applied only locally. Apply the medicine directly to the affected areas of the skin or mucous membranes. To do this, squeeze a small amount of the drug from the tube and distribute it along the wound surface with light movements.
If Solcoseryl is prescribed for the treatment of a purulent wound, then it is first cleaned, necrotic tissue removed and disinfected. Only after that apply gel. It is indicated for the treatment of fresh wound injuries when exudate is present. Usually, the procedure is carried out two to three times a day. Reviews of the Solcoseryl gel indicate its high efficiency, and against the background of its use, faster wound cleansing takes place.
Dental paste and eye gel
Dental paste is recommended for various pathologies in the oral cavity (stomatitis, erosive processes), for the treatment of gums, used for cracks in the corners of the mouth and for the lips. The medicine is applied to the surface of the mucosa slightly dried with a cotton swab. A small amount of pea-sized paste is spread on the damaged surface. This procedure is repeated three to five times a day.
In ophthalmology, a special eye gel “Solcoseryl” is used. It is used as follows: a drop of medicine is squeezed from a tube and instilled into a conjunctival sac. Manipulation is carried out up to three to four times a day.
What are the side effects?
According to doctors and patients who have used this drug, it is very well tolerated and does not have any negative effects on the body.For the entire time the drug was used, not a single case of overdose was recorded. Side effects in the form of allergic reactions of varying severity, for example, urticaria or a slight fever, can be occasionally noted.
In most cases, allergies occur after topical treatment with Solcoseryl. It is expressed by a slight burning sensation at the site of application or the occurrence of dermatitis. In this case, you need to abandon the use of the medicine and consult your doctor.
Prices and analogues
Despite the fact that "Solcoseryl" refers to an over-the-counter group of drugs, you should consult your doctor before using it. This is especially true for the injectable form of the drug.
The drug can not be called cheap. For example, for one package of ampoules (five pieces of 5 ml each), you need to give from 900 rubles, and one tube of gel (20 g) costs 340-360 rubles. (Data for December 2017).
According to clinical trials, Solcoseryl is highly safe and rarely provokes any side effects. Today it is one of the most studied drugs with a proven therapeutic effect. That is why it is included in most treatment protocols and is widely prescribed by surgeons, oculists, dentists, neurologists.
Reviews: “Leaves no scars”
In January of this year, she removed a fairly large mole on her face. The doctor prescribed to lubricate the wound with “Solcoseryl” after the crust falls off so that there is no scar on the skin, since the mole “sat” deeply. I bought a gel in a pharmacy for 240 rubles, the composition of the medicine is an original extract from the blood of young calves. Apply "Solcoseryl" to accelerate the healing of wounds, cuts, with sunburn. The gel did not cause any side effects, although allergic reactions may appear. I smeared the scar twice a day, after applying the gel, a thin tightening film appears. It is now mid-spring, and in that place where there was a mole, there was only a barely noticeable trace. If you do not look closely, it is not noticeable at all. I'm happy! I heard that Solcoseryl even helps to reduce fine wrinkles, such as crow's feet near the eyes, I tried, but did not notice much effect. And as a healing accelerator - I recommend!
Valentine https://lekotzyvy.com/preparat/s/solkoseril/
Gel Solcoseryl was bought for use in case of burns, the son very much burned his leg. I liked the drug very much, after a week the wound began to tighten and become covered with new skin. What else I really liked, the gel does not leave scars. But it turns out that women also use this gel in the fight against wrinkles. And since there was a little gel left from the burn treatment, I decided to try and I lubricate the wrinkles on my face. I'm in shock, the drug smoothes fine wrinkles for sure, I don’t know just how long it can be used. Smeared only at night with a thin layer, the gel is oily, the whole face shines. I’ve finished the tube and so far I’m not using it anyway, it’s still a medicine, not a face cream.
Diana, https://lekotzyvy.com/preparat/s/solkoseril/
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