The content of the article
"Tranexam" can not only stop bleeding, but also has an anti-tumor, anti-inflammatory, anti-allergic effect. It can be used with menopause, and during pregnancy with bleeding. It is important to know the features of taking and prescribing the medicine.
Composition and principle of action
The therapeutic effect of the drug is due to the content of tranexamic acid in the composition. The main effect of the acid is associated with the effect on blood coagulation.
Effect of taking
How much to take the drug to Truceca, what was the effect? To maintain the liquid state of blood and protect against the formation of clots, the body needs the sequential completion of the chain of biochemical reactions. One of the steps is the conversion of plasminogen to plasmin. Tranexamic acid inhibits this reaction, exerting an antifibrinolytic effect. As a result, the rate of formation of blood clots increases and bleeding stops.
Tranexamic acid has a systemic and local hemostatic effect. In addition, it is able to influence the formation of kinins - substances responsible for the severity of inflammation and allergies. Tranexamic acid has anti-allergic and anti-inflammatory effect. Its antitumor properties are also known, which are currently being studied.
When appointed
Tranexam is appointed for the following purposes:
- as a hemostatic agent - when performing any operations, as well as in case of acute bleeding in obstetric, gynecological, surgical, oncological, dental practice;
- with anti-inflammatory purpose - with tonsillitis, pharyngitis, laryngitis, stomatitis;
- as an antiallergic drugo - with eczema, urticaria, contact dermatitis, angioedema.
Indications for use of the drug are liver disease, leukemia for the prevention of possible bleeding with suspected increased bleeding.
In gynecology
In 90% of cases, Tranexam is used to stop bleeding associated with increased fibrinolysis. In gynecological practice, it is used in the following conditions:
- with heavy menstruation - at uterine fibroids, endometriosis, hyperplasia and polyps of the endometrium, with dysfunctions;
- after curettage - to reduce the discharge after abortion, miscarriage, hysteroscopy;
- with acyclic spotting - they can appear with dysfunction, while taking oral contraceptives.
During pregnancy and lactation
The drug is often used during pregnancy to stop bleeding. Its safety has not been proven in extensive studies, but long-term monitoring of women to whom it is prescribed according to indications prove the absence of a significant negative effect on the developing baby.
"Trinixan" is prescribed at any time during pregnancy and after childbirth in the form of injections or tablets. It is shown in the following situations:
- with the threat of miscarriage with spotting;
- with retrochorial hematoma (placental abruption);
- with postpartum hemorrhage;
- with manual separation of the placenta.
Also, "Tranexam" is prescribed for bleeding as a result of central or regional placenta previa. The duration of treatment should not exceed three days in women with hereditary thrombophilia, antiphospholipid syndrome, since further therapy will cause the opposite effect - termination of pregnancy.
Instructions for use "Tranexam"
Tranexam is available as a solution in ampoules of 1 ml with a tranexamic acid content of 50 mg. At home, the drug is often used in tablets, each containing 250 mg. How to drink "Tranexam" with heavy periods and use it in case of other bleeding can be seen in the table.
Table - Tranexam Application
| Oral tablets | Solution for intravenous injections |
|---|---|
| - 4-6 tablets 2-3 times a day before or after meals; - you can increase the dosage of Tranexam to 4-6 tablets 3-4 times a day; - during pregnancy, 1-2 tablets are enough 3-4 times a day | - Based on 15 mg / kg body weight; - at a rate of 1 ml / minute; - every 6-8 hours |
Who should not be used
The use of tablets "Transekam" and especially intravenous injection should be prescribed by a doctor. The drug has contraindications and side effects. Do not use the medicine when:
- recorded allergic reactions to it;
- acute thrombosis;
- high risk of thrombosis (thrombophlebitis, heart attack);
- violation of color vision;
- renal failure.
The following adverse reactions are possible while taking Tranexam:
- dyspepsia - nausea, vomiting, heartburn, decreased appetite;
- disruption of the central nervous system - dizziness, weakness, drowsiness;
- cardiovascular disorders - thrombosis, thromboembolism, decreased pressure;
- allergic manifestations - urticaria, itching, Quincke's edema, anaphylactic shock.
If you have any complaints while taking the medicine, you should immediately seek medical help. There are no data on overdose on the drug.
Other features
If you are scheduled to drink Transikam to stop menstruation or another type of bleeding, you should not combine this with the use of other hemostatic agents. Such combinations can lead to activation of thrombosis and serious complications. Also, Tranexam should not be combined with the following drugs:
- blood components;
- penicillins;
- tetracyclines;
- "Dipyridamole";
- Diazepam
- hypertensive drugs.
Analogs
Complete analogues of the drug are the following drugs:
- Trenax
- "Tugina."
The following drugs act on other mechanisms compared to Tranexam, but also give a hemostatic effect:
"Tranexam" is one of the most effective hemostatic drugs. It helps literally five minutes after intravenous administration.Especially important is a similar action during surgery. Reviews about Tranexam for uterine bleeding also prove its high efficiency and safety, subject to the rules of admission and doctor’s recommendations.
Reviews: "Powerful thing"
Tranexam is a powerful thing. I was prescribed, but I did not drink it for long, 2-3 days. I think you will also not take it for long, as soon as it stops bleeding, it will be canceled. I understand that it is unpleasant to swallow tablets with handfuls, but there is nowhere to go. And he does not harm Lyalka. Recover!
Forget-me-not https://deti.mail.ru/id1004369158/
I have placenta previa, this Monday, too, began a small discharge. I arrived at the hospital in an ambulance, there they looked and were allowed to go home, but they prescribed complete rest and tranex for 5 days, 4 tablets per day to drink. Allocations passed in the evening after taking the drug, now I feel good. Health to you!
Natalya https://deti.mail.ru/id1013684767/
Hello! I’m 15 years old, I had very abundant periods, it was pouring out of a bucket, I went to the gynecologist, she prescribed tranex, said if I don’t stop pouring, I should go to the hospital, the periods have passed, but after that I haven’t had any months .
Liana, https://www.baby.ru/u/usr1777667/
I drank the Tranixamus 2. Table 3 times a day for 3 days helped, it poured for 20 days (for durie young people I experimented with duphaston with monthly results without stopping to get rid of painful periods)
Polish ladies https://www.baby.ru/u/soleveig/
After childbirth, bleeding opened, which was never satisfied to stop. A dropper (Tranexam) was prescribed at the hospital. They made a few droppers and everything stopped. Thanks, it helped!
Marina, https://www.rlsnet.ru/comment/traneksam
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